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This study analyzed trends in skin biopsy rates between 1986 and 2001 and their association with changes in the incidence of melanoma. Study data were drawn from Medicare claims data for individuals age 65 and older that reside in one of the nine geographic areas of the U.S. National Cancer Institute's Surveillance Epidemiology and End Results (SEER) program. Based on the evidence that the increase in biopsy rates is associated with an increase in early stage melanoma diagnosis, the researchers suggest the existence of over-diagnosis rather than a true increase in the incidence of melanoma.
Key Findings: