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Prescription Drugs and Services

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Evaluating an Intervention to Reduce Unnecessary Medical Services

November 13, 2012 | Program Result Report

From November 2010 through March 2012, the California Quality Collaborative (CQC) conducted an evaluation of its regional improvement effort aimed at reducing unnecessary services and engaging physicians in improving efficiency of resource use.

Trends in Resistance to Carbapenems and Third-Generation Cephalosporins among Clinical Isolates of Klebsiella pneumoniae in the United States, 1999-2010

March 1, 2013 | Journal Article

Increases in the prevalence of drug-resistant pneumonia present a major infection control challenge for public health.

Directly Observed Antidepressant Medication Treatment and HIV Outcomes Among Homeless and Marginally Housed HIV-Positive Adults

February 1, 2013 | Journal Article

This study examines whether directly observed fluoxetine treatment may be an effective strategy to reduce depression symptom severity and improve HIV treatment outcomes.

False Claims Act Prosecution Did Not Deter Off-Label Drug Use in the Case of Neurontin

December 1, 2011 | Journal Article

Since 2004 the United States has collected approximately $8 billion from fraud enforcement actions against pharmaceutical manufacturers accused under the federal False Claims Act of illegally promoting drugs for off-label uses.

Limited Options to Manage Specialty Drug Spending

April 1, 2012 | Issue Brief

Spending on specialty drugs—typically high-cost biologics used to treat a variety of serious, complex conditions ranging from blood disorders to rheumatoid arthritis—has been growing at a persistently high rate in recent years.

Receipt of Opioid Analgesics by HIV-Infected and Uninfected Patients

January 1, 2013 | Journal Article

This cross-sectional study examined opioid analgesic receipt in HIV+ and uninfected patients to identify whether receipt varies by HIV status and to identify factors associated with opioid receipt. After adjustment, HIV+ patients were 40 percent more likely to receive opioids than uninfected patients.

Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults with Limited Prior Drug Coverage

July 27, 2011 | Journal Article

While Medicare Part D has reduced out-of-pocket expenses and increased medication use and adherence, little is known about whether the prescription drug benefit has reduced medical spending in other areas.

Origins of Medical Innovation

November 1, 2012 | Journal Article

Individual inventors and scientists involved in the early stages of medical technology development play an important role in medical innovation.

Nurses and Medication Management

December 16, 2011 | Program Result Report

Interdisciplinary research teams at four institutions examined nursing's role in - and contribution to - medication management in hospital and transitional care settings.

New Research: Treating HIV/AIDS Effectively as a Chronic Disease

January 25, 2013 | Story

Safer therapies and solid social support are needed to help people live healthier lives with HIV/AIDS.

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